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  • Hypertriglyceridemia (inherited)

    Hi there,

    I find myself in a bit of a bind. I have Hypertriglyceridemia (inherited) and have been put on fibrates, fish oil, and a high dose of statins. My numbers initially came down but I've had some side effects from the statins. Mental vagueness and hormonal upset (anyone else had this??). I'm also taking Metformin as I'm insulin resistant and have had bad PMS (PMT) in the past (really, really bad). I've also been diagnosed with Fibromyalgia. Although some initial success from the drug regime (my specialist wants cholesterol levels of under 1 and Trigs under 3 (this might be under 100 and 300 for my American friends) and they were quite low they have crept up. I noticed some terrible weight gain although my consumption doesn't seem to be increased. I've had an outbreak of skintags - which I always associate with hormonal imbalance a couple of callouses have developed on my fingers - (no idea why). Terrible gastric bloating. Moon face and buffalo hump. I had these problems in my early 20s and metformin really dealt with them but now they have returned. Meformin helped weight for a while but your body seems to get accustomed to these things. I have tried no carbs before but had terrible, TERRIBLE cravings. Especially when I was premenstural. I lost weight once and it really helped my fats (I ate a lot of nuts and seeds). My Trigs fell from 10 to 3 (naturally). Now I take a fibrate I have to start my day with bread and I find that this puts me on the back foot! If anyone can offer any advice or encouragement I would be most grateful. At one point my Trigs were 20 putting me at risk of Pancreatitis and then Pancreatic cancer if not controlled...

    Many thanks,

    Annie

  • #2
    Welcome to the forum and thank you for posting.

    It would be irresponsible to suggest that you defy the medical advice you were given. Your genetically high triglycerides may not be controllable except by restricting the transport of them. This appears to be the strategy. While it appears to run counter to Primal dietary suggestions you'll read here, your problem is medical and not simply a dietary thing you should hack or experiment with.

    I suggest you maintain your prescribed regimen but 1) add a supplement of CoQ10 (Ubiquinol) to mitigate some negative effects of the statins 2) choose krill oil over regular fish oil to diminish the high risk of oxidation and 3) eat a sourdough or non-gluten form of bread prior to your fibrates.

    Some of the skin symptoms you mentioned I associate with longterm use of seed vegetable oils. These also increase triglycerides. Therefore, the most primal thing you can do is the absolute avoidance of polyunsaturated fats from vegetable oil sources.

    Best of luck to you.
    Last edited by John Caton; 06-02-2016, 03:04 AM.
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    Old Paths ... New Journeys

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    • #3
      Originally posted by John Caton View Post
      Welcome to the forum and thank you for posting.

      It would be irresponsible to suggest that you defy the medical advice you were given. Your genetically high triglycerides may not be controllable except by restricting the transport of them. This appears to be the strategy. While it appears to run counter to Primal dietary suggestions you'll read here, your problem is medical and not simply a dietary thing you should hack or experiment with.

      I suggest you maintain your prescribed regimen but 1) add a supplement of CoQ10 (Ubiquinol) to mitigate some negative effects of the statins 2) choose krill oil over regular fish oil to diminish the high risk of oxidation and 3) eat a sourdough or non-gluten form of bread prior to your fibrates.

      Some of the skin symptoms you mentioned I associate with longterm use of seed vegetable oils. These also increase triglycerides. Therefore, the most primal thing you can do is the absolute avoidance of polyunsaturated fats from vegetable oil sources.

      Best of luck to you.
      Thanks John - I don't eat any vegetable or seed oils. Only Olive oil and butter used here (occasional beef dripping or lard). I did get my levels down once through weight loss and even with the drug regimen we did try weightloss first but on the diet they suggested weight loss was marginal and difficult to maintain. In addition cravings were sustained.

      I will try CoQ10 and Krill oil - I do mostly eat a rye bread. But will look into a sourdough instead.

      Best wishes,

      Annie.

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