No announcement yet.

Omega-6 / Omega-3 Ratio

  • Filter
  • Time
  • Show
Clear All
new posts

  • Omega-6 / Omega-3 Ratio

    "Omega six is like a fat-producing bomb." ~~ researcher

    Omega imbalance can make obesity 'inheritable': study
    July 16, 2010 by Marlowe Hood

    Overeating combined with the wrong mix of fats in one's diet can cause obesity to be carried over from one generation to the next, researchers in France reported Friday.

    Omega-6 and omega-3, both polyunsaturated fatty acids, are each critical to good health.

    But too much of the first and not enough of the second can lead to overweight offspring, the scientists showed in experiments with mice designed to mirror recent shifts in human diet.

    Over the last four decades, the ratio of omega-6 to omega-3 in a typical Western diet has shifted from a healthy five-to-one to 15-to-one in much of Europe, and up to 40-to-one in the United States.

    In the breast milk of American women, the average ratio has gone from six-to-one to 18-to-one.

    Earlier studies have established a link between such imbalances and heart disease.

    But "this is the first time that we have shown a trans-generational increase in obesity" linked to omega intake, said Gerard Ailhaud, a biochemist at the University of Nice-Sophia Antipolis and main architect of the study.

    "Omega six is like a fat-producing bomb," he told AFP by phone.

    Experts differ on whether obesity is more importantly due to the percentage of fat in one's diet or the sheer amount of calories consumed.

    The findings, published in the US-based Journal of Lipid Research, add yet another dimension to the debate, and could shed new light on the obesity epidemic that has swept across the globe, mainly in rich nations.

    They also suggest that persistence within families of health-threatening weight gain -- while not genetic in origin -- may not be entirely due to environmental factors either.

    The link between omega imbalance and obesity "is probably epigenetic," said Ailhaud, referring to the complex process whereby the information in genes is translated into chemical activity.

    "The genome and the DNA of the rodents has not been modified, but these factors can influence the way in which certain genes are expressed."

    In the experiments, four generations of mice were fed a 35-percent fat diet with the omega imbalance now found in much of the developed world.

    The result was progressively fatter mice at birth, generation after generation.

    The rodents also developed insulin-resistance, a telltale symptom for diabetes 2, one of the most common -- and debilitating -- consequences of obesity in humans.

    The equally undesirable increase in omega-6 and drop in omega-3 can be partly explained by the change from grass-fed to grain-fed livestock, Ailhaud explained.

    Grass is rich in omega-3. "But to increase productivity, feed was shifted to grain meal, especially corn, which contains a high concentration of omega-6," he said.

    Adding a small quantity of flaxseed oil to animal feed could help restore a healthy omega balance in meat and dairy products, he added.

    There are three types of fatty acids -- saturated fats, monounsaturated fats and polyunsaturated fats.

    In France, health authorities recommend that fat intake should between 30 and 40 percent of calories consumed, while the US Food and Drug Administration suggests a range of 20-to-30 percent.

    Both governments agree that most of that intake should be from polyunsaturated and monosaturated fats such as fish, nuts and vegetable oils rather than the saturated fats found in red meat and dairy products.

    (c) 2010 AFP

  • #2
    Fascinating about the mice getting fatter and fatter each generation! I wonder what it is about omega-6 that causes obesity? As in, how does that work exactly?
    I'm a quitter...but I'm back now.


    • #3
      The fuck is that last point? The last thing we need is more vegetable oils. The cognitive dissonance! It burns!

      Also I don't think that red meat should be on the government-knows-best hit list since beef is fairly low in omega 6 no matter how much awful corn you feed it.

      A few proposed ways of excessive inflammation causing obesity are inflammation of the hypothalamus which causes leptin resistance. It causes hepatic insulin resistance, and the influx of pro-inflammatory molecules like IL-6 stimulates an over-production of suppressors like SOCS-3 which blocks leptin signaling. Also cortisol i think. And plenty more I'm sure.

      Stephan has covered some of this stuff
      Stabbing conventional wisdom in its face.

      Anyone who wants to talk nutrition should PM me!


      • #4
        Yeah I agree, we definitely don't need more refined vegetable oil and considering the subject matter a pretty ignorant statement to make
        Whether you think you can..... or you think you can't..... your 100 % correct.


        • #5
          The summary point that's out of synch with the study results is just like all those studies cited in GCBC....evidence presented that sat fat doesn't cause heart disease, then a summary by the government agency saying to limit sat fat!

          Thanks for the links, Stabby. You sure are good at learning the fine points of biochemistry.
          I'm a quitter...but I'm back now.


          • #6
            Linoleic acid has Been investigated as a thyroid suppressant. You don't want to eat a lot of it!


            • #7
              Keep it simple.

              Eat lots of plants and grass-fed animals.

              Law #1 guys... we all know this!
              Find me at Cheers!


              • #8
                Yuh, that end bit is ignorant and 1/2. But, I find the business about diet-induced obesity going to the next generation pretty news-worthy.


                • #9
                  Should i seek omega 3 in an isolated form to add to my diet rather then an 6:3 supplement. I don't eat seafood.
                  Nor have i began to supplement omegas. Or since i don't supplement omegas at all, should i get a 6:3 in a supportive ratio to both supply me with something I'm probably deficient in. The 6.

                  What if any test can i take to learn my starting point and where i need to go?
                  Last edited by Styleten; 07-22-2010, 11:03 AM.